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Original Article
Clinical Observation on Hemodialysis in Children with Chronic Renal Failure.
Hae Il Cheong, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1988;31(5):590-596.   Published online May 31, 1988
There had been total 21 children with end stage renal disease in whom hemodialysis was done in the pediatric dialysis unit of Seoul National University Children’s Hospital during the period from 1986. 3. 31 to 1987. 11. 30. And we took a retrospective review of their clinical data, and the results were as follows 1) Primary glomerular disease, H enoch-Schdnlein nephritis, and reflux nephropathy were...
Acute Tumor Lysis Syndrome in Burkitt Lymphoma.
Dong Kyu Jin, Soo Jong Hong, Il Soo Ha, Hyo Seop Ahn, Yong Choi, Chang Yee Hong
Clin Exp Pediatr. 1988;31(3):362-369.   Published online March 31, 1988
To assess the tumor lysis syndrome in Burkitt lymphoma, we analyzed the clinical and laboratory findings of 17 patients with Burkitt lymphoma who were admitted to the Department of Pediatrics, Seoul National University Hospital from January 1979 to December 1986. The acute tumor lysis syndrome was diagnosed when two of the five following metabolic abnormal- ities were met: ① hyperuricemia (≥8.0mg/dl), ② hyperphosphatemia (≥5.5 mg/dl),...
A Study on Minimal Change Nephrotic Syndrome in Children.
Yong Choi, Hong Jin Lee, Hae Il Cheong, Kwang Wook Ko, Hyun Soon Lee, Yong Il Kim
Clin Exp Pediatr. 1988;31(2):220-226.   Published online February 28, 1988
To assess the clinical significance of histopathologic variants of minimal change nephrotic syn- drome (MCNS) by light microscopic findings, 148 biopsy proven MCNS patients, who were admitted to Seoul National University Hospital between the period from January 1976 to December 1986, were analyzed according to clinical findings, steroid responsiveness, and follow up status in relation to the pathologic variants. The followings are summary and conclusion. 1) Significantly...
A Case of Potter Syndrome with Bilateral Polycystic Kidneys.
Chun Hwa Lee, Jung Hwan Choi, Yong Choi, Chong Ku Yun, Yeon Lim Suh, Je G Chi, Son Moon Shin
Clin Exp Pediatr. 1987;30(11):1282-1286.   Published online November 30, 1987
In 1946, Potter described a series of 20 cases of infants in whom bilateral absence of the kidneys was associated with hypoplasia of the lungs and characteristic faces. Afterwards it has been known that any condition that causes significant reduction in urine formation or excretion will result in oligohydramnios accounts for many of the nonrenal features of Potter syndorme. We report a case...
A Clinical Observation on Systemic Lupus Erythematosus in Children.
Han Wook Yoo, Hae Il Cheong, Hoan Jong Lee, Yong Choi, Kwang Wook Ko, Yong Il Kim
Clin Exp Pediatr. 1987;30(5):527-535.   Published online May 31, 1987
To elucidate the clinical characteristics of childhood onset systemic lupus erythematosus (SLE), we carried out a retrospective review on medical records of sixteen patients who were diagnosed as SLE on the base of “the 1982 revised criteria for the SLE” (by American Rheumatism Association) at the Department of Pediatrics, Seoul National University Children’s Hospital between January 1976 and July 1986. The results were summarized...
Pheochromocytoma in Two 10-year Old Children.
Young Soo Kim, Young Hoon Kim, Se Won Yang, Yong Choi, Hyung Ro Moon
Clin Exp Pediatr. 1987;30(2):207-211.   Published online February 28, 1987
We experienced two cases of pheochromocytoma in 10 year-old boy and girl. Boy had bilateral and girl had unilateral pheochromocytoma. Both patients who were severely retarded in height growth had hypertension and one patient had cardiomyopathy. In both patients, vanillylmandelic acid in urine was increased, and phentolamine test was positive. Adrenal mass was visualized by C.T. in each ease. Successful surgical removal was done,...
Case Report
A Case of Dubin-Johnson Syndrome in Childhood.
Young Hoon Kim, Young Soo Kim, Sang Kyu Park, Jung Ki Seo, Yong Choi
Clin Exp Pediatr. 1986;29(11):1275-1280.   Published online November 30, 1986
A case of Dubin-Johnson syndrome in 10-year-old Korean male child was presented. The presenting symptom was dark-colored urine for several years. Laboratory findings showed increased bilirubin, especially direct-reacting bilirubin, and abnormal urinary coproporphyrin pattern (coproporphyrin I : 58%, coproporphyrin JK : 42%). Needle biopsy specimen of liver showed dark-brownish pigmentation in liver cells but was otherwise normal histologically.
Original Article
Chronic Renal Failure in Children.
Yong Choi, Jong Duck Kim, Kwang Wook Ko, Jae Seung Lee, Pyung Kil Kim, Ja Hoon Koo
Clin Exp Pediatr. 1986;29(5):493-497.   Published online May 31, 1986
We analyzed data on children with chronic renal failure collected from 36 pediatric training hospitals during the period from Jan. 1, 1980 to Dec. 31, 1984. The following results were obtained： 1) Total number of children with chronic renal failure during the study period was 135. The incidence was about 1 per 2,000 in-patients and 2.09 per million children under 15...
Renovascular Hypertension in Childhood.
Jae Won Song, Soo Heun Lim, Yong Choi, Kwang Wook Ko, Chang Yee Hong, Kyung Mo Yeon
Clin Exp Pediatr. 1986;29(4):381-386.   Published online April 30, 1986
The following results were obtained from a retrospective analysis of 21 cases of renovascular hypertension who were admitted to Pediatric Department, Seoul National University Hospital, during the period from January 1978 to December 1985. 1) Takayasu arteritis was the most common cause (15 out of 21, 71%), and fibromuscular dysplasia of renal artery was confirmed only in two (9.5%) cases. 2) Male...
A Clinicopathological Study on the Biopsy-proven Henoch-Schonlein Purpura Nephritis in Children.
Jong Yoon Kim, Yong Choi, Kwang Wook Ko, Young il Kim
Clin Exp Pediatr. 1986;29(3):265-276.   Published online March 31, 1986
40 patients with Henoch-Schonlein nephritis in whom a per cutaneous renal biopsy was performed at department of pediatrics, Seoul National University Hospital during the periods Jan. 1978-Jan. 1985 inclusive were analyzed in view of clinicopathological correlation. The results were as follows: 1) Of the 40 patients reviewed, 24 cases were male and 16 female. The mean age of onset was 9 years...
Primary Peritonitis in Children with Nephrotic Syndrome.
Hae Il Cheong, Whan Jong Lee, Jeong Kee Seo, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1985;28(7):695-704.   Published online July 31, 1985
Thirty episodes of primary peritonitis in 22 children with nephrotic syndrome who had admitted in the Department of Pediatrics, Seoul National University Hospital from Jan. *81 to Sept. ’84 were studied, and the results were as follows; 1)Among 22 children, male to female ratio was 16 : 6 and the mean age at the onset of peritonitis was 7.80 years (average...
Plasma Renin Activity (PRA) in Peripheral Vein and Renal Veins in Normotensive Children.
Chong Ku Yun, Hae Il Cheong, Chung Il Noh, Jung Yun Choi, Yong Choi, Kwang Wook Ko, Kyung Mo Yeon
Clin Exp Pediatr. 1985;28(6):555-563.   Published online June 30, 1985
PRA in peripheral vein, both renal veins and both inferior vena cava (JVC) both proximal and distal to the drainage of the both renal veins was measured in 80 normotensive children with no renal disease undergoing routine cardiac catheterization due to congenital heart disease which did not cause significant hemodynamic changes in most of them. And we presented the results...
Clinical Observation on Hypertension in Hospitalized Children.
Chung Il Noh, Jong Yoon Kim, Hea Il Chung, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1985;28(5):477-482.   Published online May 31, 1985
A retrospective study of 234 children with hypertension was done. Those children were selected from the admitted patients to the pediatric ward of SNUH, from Jan. 1 st, 1972 to June 30 th, 1984. Among them, 144(61.5%) exhibited renal diseases, 17(7.3%) endocrine diseases, 15(6.4%) renovascular diseases, 12(5.1%) cardiovascular diseases, 3(1.3%) esstential hypertension, 8(3.5%) miscellaneous casuses. The most common cause among...
Captopril in Children with Renovacular Hypertension.
Yong Choi, Hoan Jong Lee, Hee Young Shin, Kwang Wook Ko, Chang Yee Hong
Clin Exp Pediatr. 1985;28(1):58-67.   Published online January 31, 1985
Captopril, a kind of converting enzyme inhibitors, is a promising anti-hypertensive drug, which is developed recently, and studied mainly in adult patients. We administered captopril to 4 children with renovascular hypertension, three of them accompanied Takayasu's arteritis and the remainder had isolated lesion. Three to five times of initial trials were performed on each patient with 12.5 mg of captopril....
Idiopathic Membranoproliferative Glomerulonephritis in Children.
Hae Il Cheong, Hee Shang Youn, Whan Jong Lee, Yong Choi, Kwang Wook Ko, Yong Il Kim
Clin Exp Pediatr. 1985;28(1):45-57.   Published online January 31, 1985
Among total 452 children with percutaneous kidney needle biopsy due to renal disease in the Department of Pediatric, Seoul National University Hospital, from Jan. 75 to Nov.84, 20(4.4%) were confirmed as embranoproliferative glomerulonephritis(MPGN) histopathologically. And 4 out of these 20 were excluded from this report because of association of systemic disease. A review of clinical and pathological findings of the...
Case Report
Rifampin Induced Nonresponsiveness to Steroid Therapy in Children with Minimal Change Nephrotic Syndrome .
Hae Il Cheong, Sang Bok Suk, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1984;27(5):506-510.   Published online May 31, 1984
We experienced three children with the biopsy proven minimal change nephrotic syndrome who had failed to respond to prednisolone, 60 mg/m2/d for 4 to 9 weeks due to concomittent administration of rifampin. Because rifampin is a known enzyme inducer of the liver like phenobarbital and dilantin which can increase the clearance of the other drugs such as steroid etc., rifampin were...
Acute Tumor Lysis Syndrome.
Sun Oak Park, In Sil Lee, Hyp Seop Ahn, Yong Choi
Clin Exp Pediatr. 1984;27(3):303-312.   Published online March 31, 1984
To assess the incidence and the effectiveness of preventive measures for tumor lysis syndrome, we analyzed the serial electrolytes levels in leukemia (Group A, 15 patients) and in lymphoma (Group B, 8 patients) patients. The results were 1)Serum LDH were elevated in all of the patients before the chemotherapy. 2)Serum uric acid were also elevated in 8 patients (A 5, B...
Original Article
Clinical Observation about complications(Especially about Mortality Cases) in Childhood Primary Nephrotic Syndrome.
Hae ll Cheong, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1984;27(3):246-252.   Published online March 31, 1984
Among 350 children who had been admitted to the Ward of Pediatrics, Seoul National University Hospital during the period from 1975.1.1. to 1983.12.31. and had been diagnosed as idiopathic nephrotic syndrome, total 21 cases (6%) had expired or had progressed into end stage renal disease during follow-up. Among these, 13 cases(61.9%； Group A) had expired due to chronic renal failure...
Clinical Significance of Selectivity Index in Nephrotic Syndrome.
Hoan Jong Lee, Hee Jin Kim, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1984;27(1):68-73.   Published online January 31, 1984
Slectivity I nd ices (CIgG/Ctransf erri n) of 114 nephrotic children, who were admitted to the Pediatric ward of SNUH from January, 1979 to December 1982, were, analyzed in relation to pathology, response to steroid treatment and the variability in the individual patients. In Summary 1)83% of MPGN, and 74% of FSGS showed S.I of more than 0.2 while 36%...
Statistical Observation for Pediatric Inpatients.
Keun Chan Sohn, Sung Sook Cho, Kwang Chan Doh, Yong Choi, Ki Sub Chung, Dong Hyuk Kum, Sung Taek Kim
Clin Exp Pediatr. 1984;27(1):1-8.   Published online January 31, 1984
We observed patients admitted to the department of Pediatrics of 24 general hospitals in Korea during the past five years from Jan. 1976 to Dec. 1980 and classified them, by year & disease according to the International Classification of Disease by W.H.O.(1965 Revision). The results were as follows: 1)The total number of pediatric inpatients was 138,136 with about 10% yearly...
Renal Disease in Children-A Ten-Years Experience.
Hee Young Shin, Hae Il Cheong, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1983;26(7):681-686.   Published online July 31, 1983
Statistical analysis of inpatients of Seoul National University Hospital from 1972 to 1981 who had renal diseases was performed with respect to their disease pattern, annual incidence of each disease, and age distribution. From 1972 to 1981 renal disease was found in 831 patients among 11,226 total inpatients (7.4%). Male to female ratio of renal disease patients was 2.2 to 1, while male to...
Clinical Observation of Juvenile Diabetes Millitus.
Hae Il Cheong, Dong Gyoon Kim, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1983;26(6):553-563.   Published online June 30, 1983
Clinical data of 33 children with juvenile diabetes mellitus who were admitted to the Seoul National University Hospital from Jan. 1967 to Feb. 1983 were analyzed retrospectively. Male to female ratio was 10:23, the mean age at onset was 6 10/12 years, and there was considerable seasonal variation with peaks in late winter and spring. Polyuria and polydipsia were noted in all cases as...
Case Report
A Case Report Kostmann Syndrome.
Han Wook Yoo, Son Moon Shin, Hyo Seop Ahn, Yong Choi, Chang Yee Hong
Clin Exp Pediatr. 1983;26(3):284-288.   Published online March 31, 1983
Kostmann syndrome (Infantile genetic agranulocytosis), a disease characterized by recurrent infections leading to death in infancy, shows an agranulocytosis with variable monocytosis, eosinophilia in the peripheral blood, accompanied by the maturation arrest of the myelocytic series at the promyelocyte-myelocyte level. A 2 years 3 month old female patient with Kostmann syndrome is reported, who has suffered from recurrent infections since 1 month of age. During...
Original Article
Lipoprotein Profiles in Minimal Change Nephrotic Syndrome.
Yong Choi, Heui Jeen Kim, Hae Il Cheong, Jeong Kee Seo, Kwang Wook Ko
Clin Exp Pediatr. 1983;26(3):237-246.   Published online March 31, 1983
Data obtained from 59 hospitalized patients with minimal change nephrotic syndrome which was confirmed by kidney biopsy, were analyzed for serum albumin, serum lipids, 24hr urine protein, creatinine clearanee, HDL-eholesterol. In 38 of the patients, lipoproteins were analyzed. The following results were obained 1. Serum phospolipid (PL) was increased whenever serum total cholesterol (TC) was increased but to a lesser degree. The ratio of TC/PL were...
Pericardial Effusion in Patients with Rheumatic Fever.
In Suck Seo, Hee Ju Kim, Jae Ho Lee, Yong Soo Yoon, Yong Choi, Chang Yee Hong
Clin Exp Pediatr. 1982;25(12):1225-1233.   Published online December 31, 1982
Pericarditis denotes worse prognosis in patients with rheumatic fever. During the period of 4 years from Jan. 1978 to Dec. 1981, one hundred and eighteen patients were diagnosed as rheumatic fever on the basis of revised Jones* criteria. One hundred and one patients of them were evaluated with M-mode echocardiography, and were analysed according to Horo- witz^ classification of pericardial effusion. The results were as...
Case Report
Pancreatic Pseudocysts and Ascites as Complications of Chronic Pancreatitis.
Nam Su Kim, Hee Ju Kim, Kyoo Duck Lee, Yong Choi, Hyung Ro Moon
Clin Exp Pediatr. 1982;25(2):183-189.   Published online February 28, 1982
A case of pancreatic pseudocysts and bloody pancreatic ascites as complications of chronic pancreatitis in eleven-year-old girl was reported. She was admitted to the pediatric ward with chief complaints of abdominal distension and bloody ascites. About nine months prior to admission, when she was stuck by a bicycle, she had sustained a blow on her abdomen. She has been apparently...
Original Article
The Incidence of HBs Antigenemia in Glomerular Desease and Control Group in Children.
Yong Choi, Whan Jong Lee, Jeong Kee Seo, Kwang Wook Ko
Clin Exp Pediatr. 1981;24(2):122-127.   Published online February 15, 1981
HBsAg, HBcAb and HBsAb were examined with radio-immunoassay in 265 patients with glomerular disease, who were admitted to wards or visited to outpatient clinics of department of pediatrics, Seoul National University Hospital, from Jan., 78 to Oct. 80, and in 576 control group, with other than liver disease and without history of transfusion. The incidence in glomerular disease was 10.2%(27...
Case Report
Late Hemorrhagic Disease of Infancy.
Joong Gon Kim, Young Min Ahn, Hyo Seop Ahn, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1980;23(7):572-577.   Published online July 15, 1980
A hemorrhagic disease due to prothrombin complex deficiency os described in 4 infants from 1 to 11 months of age. This disease is different from the hemorrhagic disease of the newborn. The main differences are that it is found in an older age group and that intracranial hemorrhages are frequent. Rapid clinical and laboratory response after vitamin K therapy are...
Original Article
Long Term Follow-up Study of Chidren with nephrotic Syndron (over 5years).
Hae Il Cheong, Whan Chong Lee, Yong Choi, Cwang wook Ko
Clin Exp Pediatr. 1980;23(2):130-142.   Published online February 15, 1980
Follow-up study of fifty two children with nephrome who had once admitted to the pediatric ward of S.N.U.H were presented with regards to response to initial steroid therapy, relapsing patterns, and factors affecting prognosis. All patients were followed up for more than 5 years and the mean period of follow-up was 7 7/12 years, and in two patients, follow-up for...
Case Report
A Case of Chylous Ascites in an Infant Boy.
Kyu Chan Kim, Hae Il Cheong, Yong Choi, Hyung Ro Moon
Clin Exp Pediatr. 1980;23(1):63-67.   Published online January 15, 1980
The authors report a case of chylous ascites in a two month old boy with massive ascites. He was managed with repeated therapeutic paracentesis and skimmed milk feeding. A marked improvement was resulted in clinical symptoms and laboratory findings at the time of discharge to be followed-up at the outpatient service. A brief review of literatures is included
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